NDLI: N-Heterocyclic carbene-catalyzed chemoselective cross-aza-benzoin reaction of enals with isatin-derived ketimines: access to chiral quaternary aminooxindoles.

Content Provider	Semantic Scholar
Author	Xu, Jianfeng Mou, Chengli Zhu, Tingshun Song, Bao-An Chi, Yonggui Robin
Copyright Year	2014
Abstract	A chemo- and enantioselective cross-aza-benzoin reaction between enals and isatin-derived ketimines is disclosed. The high chemoselectivity (of the acyl anion reaction over enal α- and β-carbon reactions) is enabled by the electronic and steric properties of the N-heterocyclic carbene organocatalyst.
File Format	PDF HTM / HTML
DOI	10.1021/ol501286e
PubMed reference number	24877668
Journal	Medline
Volume Number	16
Issue Number	12
Alternate Webpage(s)	http://www3.ntu.edu.sg/home/robinchi/publication%20lists/44%20pdf.pdf
Alternate Webpage(s)	https://doi.org/10.1021/ol501286e
Journal	Organic letters
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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