NDLI: The impact of prophylactic treatment on post-traumatic epilepsy after severe traumatic brain injury.

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The impact of prophylactic treatment on post-traumatic epilepsy after severe traumatic brain injury.

Content Provider	Semantic Scholar
Author	Formisano, Rita Barba, Carmen Buzzi, Maria Gabriella Newcomb-Fernandez, Jennifer K. Menniti-Ippolito, Francesca Zafonte, Ross Vinicola, Vincenzo Spanedda, Francesca
Copyright Year	2007
Abstract	AIM To assess the incidence of late post-traumatic epilepsy (PTE) in patients with very severe traumatic brain injury (TBI) who either received or did not receive anti-epileptic prophylactic treatment. METHODS Two populations were studied: 55 patients retrospectively and 82 subjects prospectively. RESULTS Ten patients (18%) in the first population showed late PTE. Although the incidence was lower in patients who did not receive prophylactic treatment, the difference between the treated and the non-treated group was not statistically significant. Sixty-nine patients in the second group (84%) had prophylactic treatment. Twenty-seven patients (39%) suffered from late PTE during the 2-year follow-up period and 17 of them (63%) showed EEG epileptic abnormalities. No patient who did not receive preventive therapy suffered from late PTE during the observation period. CONCLUSIONS Due to the negative cognitive effects of anti-epileptic drugs, the preliminary results are of considerable interest for the rehabilitation of patients with very severe TBI.
Starting Page	499
Ending Page	504
Page Count	6
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.hello.nhs.uk/documents/lit_search_archive/2015/Incidence%20of%20fits%20in%20adults%20with%20severe%20traumatic%20brain%20injury.pdf
PubMed reference number	17522989v1
Volume Number	21
Issue Number	5
Journal	Brain injury
Language	English
Access Restriction	Open
Subject Keyword	Borg Category-Ratio 10 Perceived Exertion Score 7 Brain Injuries Condoms, Unspecified Congenital Abnormality Epilepsy Epilepsy, Post-Traumatic Mental Suffering Patients Traumatic Brain Injury
Content Type	Text
Resource Type	Article

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