NDLI: El ciclo celular y su papel en la biología de las células progenitoras hematopoyéticas

Content Provider	Semantic Scholar
Author	Alvarado-Moreno, J. Antonio Mayani, Héctor
Copyright Year	2007
Abstract	El ciclo celular constituye el conjunto de eventos que determinan la actividad metabolica de toda celula asi como su division y la generacion de celulas hijas. Este proceso esta involucrado en todos los procesos celulares tales como proliferacion y diferenciacion. Se ha demostrado que diversos elementos moleculares participan en su regulacion y que alteraciones en este proceso pueden conducir a trastornos fisiologicos e incluso a la muerte del organismo. En los mamiferos, uno de los tejidos con mayor recambio celular es el hematopoyetico, por lo que se requiere un control muy estricto del ciclo celular, principalmente a nivel de celulas troncales y progenitoras para la optima produccion de celulas sanguineas. En este articulo presentamos un panorama general de los principales mecanismos y factores involucrados en la regulacion del ciclo celular, poniendo particular enfasis en su papel en la biologia de las celulas hematopoyeticas primitivas.
Starting Page	149
Ending Page	161
Page Count	13
File Format	PDF HTM / HTML
Volume Number	143
Alternate Webpage(s)	http://www.medigraphic.com/pdfs/gaceta/gm-2007/gm072h.pdf
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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