Loading...
Please wait, while we are loading the content...
Similar Documents
Small coronary calcium deposits and elevated plasma levels of oxidized low density lipoprotein are characteristic of acute myocardial infarction.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Ehara, Shoichi Naruko, Takahiko Shirai, Naoya Itoh, Akira Hai, Eishu Sugama, Yoshimi Ikura, Yoshihiro Ohsawa, Masahiko Okuyama, Takuhiro Shirai, Nobuyuki Yamashita, Hajime Itabe, Hiroyuki Haze, Kazuo Yoshiyama, Minoru Ueda, Makiko |
| Copyright Year | 2008 |
| Abstract | AIM Predictions of the onset of acute myocardial infarction (AMI) in high risk individuals are of great clinical importance. Among various risk factors, elevated levels of oxidized low density lipoprotein (ox-LDL) in plasma have been shown to reflect unstable coronary plaques. Coronary calcification is a common finding in the elderly, however, its clinical implications as a risk factor for plaque rupture are controversial. This study was designed to investigate the clinical implications of plasma ox-LDL levels and coronary calcification detected by electron-beam computed tomography (EBCT), by comparing patients with AMI with those with stable angina pectoris (SAP). METHODS We measured plasma ox-LDL levels in AMI (n=34) and SAP (n=49) patients. In addition, a coronary calcium score was quantified with the Agatston system. The total coronary calcium score (TCS) was defined as the sum of the scores for each lesion. RESULTS TCS and total calcium area were significantly smaller in patients with AMI than in those with SAP. On the other hand, plasma ox-LDL levels were significantly higher in AMI patients than in SAP patients (p<0.0005). CONCLUSION These results suggest that a combined assessment of coronary calcium and plasma ox-LDL levels may be useful for screening patients with unstable coronary plaques. |
| Starting Page | 75 |
| Ending Page | 81 |
| Page Count | 7 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://www.jstage.jst.go.jp/article/jat/15/2/15_E523/_pdf/-char/en |
| PubMed reference number | 18469488v1 |
| Volume Number | 15 |
| Issue Number | 2 |
| Journal | Journal of atherosclerosis and thrombosis |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Acute myocardial infarction Angina Pectoris Calcinosis Coronary Artery Disease Coronary artery calcium score Dental Plaque Low-Density Lipoproteins Mandibulofacial Dysostosis Patients Rupture Senile Plaques Stable angina Unstable Medical Device Problem X-Ray Computed Tomography |
| Content Type | Text |
| Resource Type | Article |
