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The effect of acute changes in coronary blood flow on left ventricular end-diastolic wall thickness. An echocardiographic study.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Gaasch, William H. Bernard, Sheilah A. |
| Copyright Year | 1977 |
| Abstract | The effect of acute alterations in coronary blood flow (CBF) on left ventricular (LV) end-diastolic wall thickness was measured by reflected ultrasound in twelve anesthetized dogs. During five minutes of coronary ligation, wall thickness decreased from a control of 9.0 +/- 0.3 mm to 8.1 +/- 0.3 mm (P less than 0.001); during reperfusion (reactive hyperemia), wall thickness was greater than control (10.2 +/- 0.2 mm at one minute, P less than 0.001). Increased CBF produced by intracoronary nitroglycerin or papaverine resulted in transient increases in wall thickness from 8.9 +/- 0.1 mm to 9.7 +/- 0.2 at one minute (P less than 0.001) and 10.0 +/- 0.6 mm to 11.2 +/- 0.7 mm at one minute (P less than 0.001), respectively. The observed direct relation between CBF and wall thickness suggests a dynamic role for CBF in calculations of LV mass, diastolic wall stress, and myocardial stiffness constants. |
| File Format | PDF HTM / HTML |
| PubMed reference number | 409570 |
| Journal | Medline |
| Volume Number | 56 |
| Issue Number | 4 |
| Part | 1 |
| Alternate Webpage(s) | http://circ.ahajournals.org/content/circulationaha/56/4/593.full.pdf |
| Alternate Webpage(s) | http://circ.ahajournals.org/content/circulationaha/56/4/593.full.pdf?download=true |
| Alternate Webpage(s) | https://doi.org/10.1161/01.CIR.56.4.593 |
| Journal | Circulation |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
