NDLI: High-affinity nerve growth factor receptor (Trk) immunoreactivity is localized in cholinergic neurons of the basal forebrain and striatum in the adult rat brain

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High-affinity nerve growth factor receptor (Trk) immunoreactivity is localized in cholinergic neurons of the basal forebrain and striatum in the adult rat brain

Content Provider	Semantic Scholar
Author	Steininger, Teresa L. Wainer, Bruce H. Klein, Rudiger Barbacid, Mariano Palfrey, H. Clive
Copyright Year	1993
Abstract	Trk-immunoreactivity was observed in basal forebrain and striatal cholinergic neurons, whereas low-affinity NGF receptor immunoreactivity was observed in basal forebrain but not striatal cholinergic neurons. Since NGF exerts trophic actions on both basal forebrain and striatal cholinergic populations, the presence of Trk in these neurons lends strong support for an essential role of Trk in NGF-responsive neurons, but suggests that the low affinity receptor is not necessary for NGF actions in the striatum.
Starting Page	330
Ending Page	335
Page Count	6
File Format	PDF HTM / HTML
DOI	10.1016/0006-8993(93)91681-H
Alternate Webpage(s)	https://api.elsevier.com/content/article/pii/000689939391681H
Alternate Webpage(s)	https://www.sciencedirect.com/science/article/pii/000689939391681H?dgcid=api_sd_search-api-endpoint
PubMed reference number	8330208
Alternate Webpage(s)	https://doi.org/10.1016/0006-8993%2893%2991681-H
Journal	Medline
Volume Number	612
Journal	Brain Research
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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