NDLI: Problems in Psychiatric Genetic Research: A Reply to Faraone and Biederman.

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Problems in Psychiatric Genetic Research: A Reply to Faraone and Biederman.

Content Provider	Semantic Scholar
Author	Joseph, Jay Ashvin
Copyright Year	2000
Abstract	Abstract A previous paper (Joseph, 2000) discussed the lack of evidence supporting genetic influences on behaviors given the label “attention-deficit hyperactivity disorder” (ADHD). Faraone and Biederman (2000) subjected this paper to a critical analysis, writing that Joseph's review “is based on errors in scientific logic compromised by an incomplete review of relevant data.” The present paper answers the most important criticisms by Faraone and Biederman. It is reiterated that possible genetic and environmental influences in both ADHD family and twin studies are confounded, and therefore no inferences about genetic factors can be drawn from these studies. In addition, several invalidating flaws of ADHD adoption studies are briefly reviewed. Problems with ADHD segregation analyses and molecular genetic studies are also highlighted. These studies were mentioned by Faraone and Biederman in the context of Joseph's alleged “incomplete literature review.” Additional topics include the appropriateness of using psychotropic drugs to treat children diagnosed with ADHD, past social and political misuse of the findings of genetic research, and alternative explanations for ADHD-type behavior. It is concluded that Joseph's previous position—that the available evidence does not support a genetic basis for ADHD—is sustained.
Starting Page	582
Ending Page	593
Page Count	12
File Format	PDF HTM / HTML
DOI	10.1006/drev.2000.0518
Volume Number	20
Alternate Webpage(s)	http://www.jayjoseph.net/files/ADHD_Reply.pdf
Alternate Webpage(s)	https://doi.org/10.1006/drev.2000.0518
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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