NDLI: Dual-channel Dual-electrode Microchip Electrophoresis with Electrochemical Detection for Voltammetric Identification of Cellular Nitrosative and Oxidative Stress Markers

Content Provider	Semantic Scholar
Author	Lunte, Susan M. Gunasekara, Dulan B. Pichetsurnthorn, Pann Santos, Diógenes Meneses Dos
Copyright Year	2014
Abstract	This paper describes the development of a dual-channel microchip in a dual-parallel electrode configuration for voltammetric characterization of analytes in real time. The microchip system contains two distinct separation channels, each having a platinum working electrode set at a different potential. Two separate electropherograms were recorded and current ratios were generated based on the current responses of analytes obtained at the two potentials. The current ratio is different for species with different half-wave potentials. This device was first used for evaluation of the purity of commercially available peroxynitrite (ONOO) standards and then for voltammetric characterization of prooxidant species in cell lysates.
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.rsc.org/images/loc/2014/PDFs/Papers/013_0463.pdf
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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