NDLI: The Effect of Lupinus Albus (Termis) and Hyphaene Thebaica (Doum) on Some Biochemical Parameters in Streptozotocin-Induced Diabetic Rats

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The Effect of Lupinus Albus (Termis) and Hyphaene Thebaica (Doum) on Some Biochemical Parameters in Streptozotocin-Induced Diabetic Rats

Content Provider	Semantic Scholar
Author	Tohamy, Amany A. Mohammed, Rasha Salah Abdalla, Mohga Shafik Ibrahim, Adel K. Mahran, Khaled F.
Copyright Year	2013
Abstract	Background: Several plants have been used as dietary adjuvant and in treating the number of diseases because of their perceived effectiveness, minimal side effects in clinical experience and relatively low costs. The present study focuses on evaluating the effect of Lupinus albus (termis) and Hyphaene thebaica (doum) on STZ-diabetic rats at the level of some biochemical parameters Material and methods: STZ was injected intraperitoneally at a single dose of 50 mg/kg to induce diabetes. Termis seeds suspension (75 mg/100 g b.wt.) was daily orally administered. Doum palm fruit suspension was daily orally administered (1g/kg b.wt.) and also gliclazide (reference drug) was administered of a dose equivalent to the therapeutic dose of rat. After four weeks of administration, blood samples were collected for biochemical measurement. Results: Blood glucose level was significantly increased. Diabetes increased serum total lipids, cholesterol, triglycerides and LDL but serum HDL was decreased. Also activities of serum enzymes ASAT, ALAT, ALP, GGT and LDH were elevated. However, L. albus and H. thebaica improved the level of mostly all biochemical parameters. Conclusion: It is concluded that termis and doum may be dietary adjuvant in reducing the harmful of diabetes.
Starting Page	789
Ending Page	794
Page Count	6
File Format	PDF HTM / HTML
DOI	10.12816/0001640
Volume Number	53
Alternate Webpage(s)	https://ejhm.journals.ekb.eg/article_15831_59229b441cc66e82e6e915fdd445857d.pdf
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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