NDLI: Inositol phosphates and phytic acid as inhibitors of biological calcification in the rat.

Content Provider	Semantic Scholar
Author	Berg, Catharina J. M. G. Van Den Hill, Lucille Stanbury, S. William
Copyright Year	1972
Abstract	1. Partial hydrolysates of phytic acid, containing mixtures of different polyphosphate esters of inositol, have been shown to be potent inhibitors of the calcification in vitro of ricketic rat cartilage and rat aorta; phytate itself was inert. 2. Phytic acid, as well as its hydrolysates, when injected parenterally, prevented aortic calcification in rats with vitamin D intoxication. 3. The rat appears able to dephosphorylate parenterally administered phytate. It may be necessary to reconsider the biological role of phytate.
Starting Page	227005
Ending Page	227005
Page Count	1
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.clinsci.org/content/ppclinsci/43/3/377.full.pdf
PubMed reference number	5077515v1
Volume Number	43
Issue Number	3
Journal	Clinical science
Language	English
Access Restriction	Open
Subject Keyword	Calcification of the aorta Calcinosis Cholesterol Esters Inositol Phosphates Phytate Phytic Acid Polyphosphates Vitamin D inorganic phosphate mixture
Content Type	Text
Resource Type	Article

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