NDLI: Inflammatory Bowel Disease Increases the Risk of Peripheral Arterial Disease

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Inflammatory Bowel Disease Increases the Risk of Peripheral Arterial Disease

Content Provider	Semantic Scholar
Author	Lin, T. T. Chen, Yu-guang Lin, Cheng-Li Huang, Wen-Sheng Kao, C. Z.
Copyright Year	2015
Abstract	Studies on the association between inflammatory bowel disease (IBD) and peripheral arterial disease (PAD) are scant. This nationwide population-based cohort study assessed the relationship between IBD and further risk of PAD.This nationwide population-based cohort study was based on data obtained from the Taiwan National Health Insurance Database from 2000 to 2010, with a follow-up period extending to the end of 2011. We identified inpatients with newly diagnosed IBD by using International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes. In addition, we selected a comparison cohort from the inpatient claims that was randomly frequency-matched according to age, sex, and index year. We analyzed the risks of PAD by using Cox proportional hazards regression models, including sex, age, and comorbidities.A total of 11,067 IBD patients and 43,765 controls were enrolled in this study. The risk of developing PAD was 1.29-fold in the patients with IBD compared with the comparison cohort, after age, sex, and comorbidities were adjusted. The patients with IBD who required 2 or more hospitalizations per year were nearly 27.5-fold more likely to have PAD compared with the comparison cohort.This nationwide population-based cohort study demonstrated that PAD risks are higher in patients with IBD compared with those inpatients without IBD. Careful follow-up observation and aggressive effective treatment should be sought for patients with IBD to reduce the risk of PAD.
Starting Page	573
Ending Page	621
Page Count	49
File Format	PDF HTM / HTML
PubMed reference number	26717386v1
Alternate Webpage(s)	https://doi.org/10.1097/MD.0000000000002381
DOI	10.1097/md.0000000000002381
Journal	Medicine
Volume Number	94
Language	English
Access Restriction	Open
Subject Keyword	Arteriopathic disease Hospitalization ICD-9-CM Inflammatory Bowel Diseases Intestinal Diseases Intestines Irritable Bowel Syndrome Patients Peripheral Arterial Diseases Peripheral Vascular Diseases inpatient
Content Type	Text
Resource Type	Article

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