Loading...
Please wait, while we are loading the content...
Similar Documents
Micafungin at physiological serum concentrations shows antifungal activity against Candida albicans and Candida parapsilosis biofilms.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Guembe, María Guinea, Jesús Marcos-Zambrano, Laura Judith Fernández-Cruz, Ana Peláez, Teresa Muñoz, Patricia Bouza, Emilio |
| Copyright Year | 2014 |
| Abstract | We assessed the in vitro activity of micafungin against preformed Candida biofilms by measuring the concentration of drug causing the most fungal damage and inhibition of regrowth. We studied 37 biofilm-producing Candida spp. strains from blood cultures. We showed that micafungin was active against planktonic and sessile forms of Candida albicans strains and moderately active against Candida parapsilosis sessile cells. Concentrations of micafungin above 2 μg/ml were sufficiently high to inactivate regrowth of Candida sessile cells. |
| File Format | PDF HTM / HTML |
| DOI | 10.1128/AAC.02738-14 |
| PubMed reference number | 24957821 |
| Journal | Medline |
| Volume Number | 58 |
| Issue Number | 9 |
| Alternate Webpage(s) | http://aac.asm.org/content/58/9/5581.full.pdf?legid=aac%3B58/9/5581&related-urls=yes |
| Alternate Webpage(s) | http://aac.asm.org/content/58/9/5581.full.pdf |
| Alternate Webpage(s) | https://doi.org/10.1128/AAC.02738-14 |
| Journal | Antimicrobial agents and chemotherapy |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |