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Circus movement within the AV node as a basis for supraventricular tachycardia as shown by multiple microelectrode recording in the isolated rabbit heart.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Janse, Michiel J. Capelle, F. J. L. Van Freud, Géza Durrer, Dirk |
| Copyright Year | 1971 |
| Abstract | Supraventricular tachycardia in an isolated rabbit heart preparation was repeatedly initiated and terminated by carefully timed atrial premature beats. Transmembrane action potentials of AV nodal cells were recorded simultaneously by a "brush electrode" consisting of 10 microelectrodes. Surface electrograms of atrium and His bundle were also recorded. The moments of activation of 54 different AV nodal cells, both during regular driving of the atrium and during tachycardia were ascertained. Premature atrial beats introduced during tachycardia would either "reset" the tachycardia or terminate it. The sequence of activation of the AV nodal cells when initiating tachycardia, during tachycardia itself, and when premature beats were interpolated during tachycardia warrant the conclusion that a circus movement in the AV node, based on functional longitudinal dissociation of the upper AV node, was the underlying mechanism of the arrhythmia. |
| Starting Page | 755 |
| Ending Page | 763 |
| Page Count | 9 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://circres.ahajournals.org/content/circresaha/28/4/403.full.pdf |
| PubMed reference number | 5551890v1 |
| Volume Number | 28 |
| Issue Number | 4 |
| Journal | Circulation research |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Action Potentials Anatomic Node Anteroventral Thalamic Nucleus Atrial Fibrillation Atrial Premature Complexes Bundle-Branch Block Heart Atrium Heart valve disease Microelectrodes Premature Cardiac Complex Sinoatrial Node Supraventricular tachycardia |
| Content Type | Text |
| Resource Type | Article |