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Characterization of the DNA gyrase from the thermoacidophilic archaeon Thermoplasma acidophilum.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Yamashiro, Kan Yamagishi, Akihiko |
| Copyright Year | 2005 |
| Abstract | Thermoplasma acidophilum is sensitive to the antibiotic drug novobiocin, which inhibits DNA gyrase. We characterized DNA gyrases from T. acidophilum strains in vitro. The DNA gyrase from a novobiocin-resistant strain and an engineered mutant were less sensitive to novobiocin. The novobiocin-resistant gyrase genes might serve as T. acidophilum genetic markers. |
| File Format | PDF HTM / HTML |
| DOI | 10.1128/JB.187.24.8531-8536.2005 |
| PubMed reference number | 16321962 |
| Journal | Medline |
| Volume Number | 187 |
| Issue Number | 24 |
| Alternate Webpage(s) | http://jb.asm.org/content/187/24/8531.full.pdf |
| Alternate Webpage(s) | http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.546.5513&rep=rep1&type=pdf |
| Journal | Journal of bacteriology |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |