NDLI: The Release of Doxorubicin ’ s Active Ingredient from the Hydrogels with Poly ( HEMA / Acrylamide / Itaconic acid ) and Their Biological Function

Please wait, while we are loading the content...

The Release of Doxorubicin ’ s Active Ingredient from the Hydrogels with Poly ( HEMA / Acrylamide / Itaconic acid ) and Their Biological Function

Content Provider	Semantic Scholar
Author	Kariper, Ishak Afşin
Copyright Year	2017
Abstract	In this study, Poly (HEMA/Acrylamide/ Itaconic acid) (HAI) polymer was synthesized for using in the release of Doxorubicin drug. Poly (HEMA/acrylamide/Itaconic acid) (HAI) hydrogel was prepared by a radical addition reaction in aqueous media formed by HEMA, acrylamide, Itaconic acid, in the presence of TEMED (N,N,N’,N’-tetramethylenediamine). The characterization of the polymer was performed by FTIR analysis. At the same time, swelling and drug absorption capabilities of the polymers were analyzed. It has been observed that the entire drug, which was added to the solution with 0.1 mg of polymer, was absorbed in around 25 hours. This measurement showed that the absorption of this polymer is quite high compared to many polymers in the literature. Moreover, this polymer showed 80% swelling at 1000 minutes. In the light of these results, it has been concluded that this new polymer is very suitable for the release of Doxorubicin drug.
File Format	PDF HTM / HTML
Alternate Webpage(s)	https://www.ijper.org/sites/default/files/10.5530ijper.51.3.67.pdf
Language	English
Access Restriction	Open
Subject Keyword	2-hydroxyethyl methacrylate 3D film Acrylamide Chemistry, Physical Doxorubicin Drug Liberation Edema Hydrogel Hydrogels One Thousand Poly A Polymer Polymers Scientific Publication Spectroscopy, Fourier Transform Infrared itaconic acid poly ICLC
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in