Loading...
Please wait, while we are loading the content...
Similar Documents
Complexity of subcortical structures 4 5 6 7 Age-related differences in the structural complexity 8 of subcortical and ventricular structures 9 10
| Content Provider | Semantic Scholar |
|---|---|
| Author | Madan, Christopher R. Kensinger, Elizabeth A. |
| Copyright Year | 2018 |
| Abstract | 27 It has been well established that the volume of several subcortical structures decreases in relation 28 to age. Different metrics of cortical structure (e.g., volume, thickness, surface area, gyrification) 29 have been shown to index distinct characteristics of inter-individual differences; thus, it is 30 important to consider the relation of age to multiple structural measures. Here we compare age31 related differences in subcortical and ventricular volume to those differences revealed with a 32 measure of structural complexity, quantified as fractal dimensionality. Across three large 33 datasets, totalling nearly 900 individuals across the adult lifespan (18-94 years old), we found 34 greater age-related differences in complexity than volume for the subcortical structures, 35 particularly in the caudate and thalamus. The structural complexity of ventricular structures was 36 not more strongly related to age than volume. These results demonstrate that considering shape37 related characteristics improves sensitivity to detect age-related differences in subcortical 38 structures. 39 40 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://eprints.nottingham.ac.uk/49069/1/20161018b_draft_clean.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
