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Multinuclear Magnetic Resonance Imaging and NMR Spectroscopy in Biomedical Investigations
| Content Provider | Semantic Scholar |
|---|---|
| Author | Pirogov, Yury A. |
| Copyright Year | 2016 |
| Abstract | Abstract Biomedical investigations with small animals using 0.5-T and 7-T MRI scanners adjusted on the Larmor frequencies of different nuclei 1 H, 2 H, 11 B, 13 C, 19 F, 23 Na, 31 P, 35 Cl are described. Experiments on registration of signals 19F from the fluorocarbons injected in laboratory animals are discussed. They give presentation on the application of fluorocarbon compounds as blood substitutes and contrasting preparations in MRI diagnostics. A blood substitute product fluorocarbon Perfluoranum® has shown effectiveness in oxygen delivery to the tissues of living organisms, and cardioprotective effect which does not depend on the patient's blood group. Inclusion of paramagnetic atoms (gadolinium, iron, etc.) to the Perfluoranum® chemical formula creates a new compounds with high MRI contrast efficiencies at Larmor frequencies of protons so and fluorine-19 nuclei. |
| Starting Page | 3 |
| Ending Page | 7 |
| Page Count | 5 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/j.phpro.2016.05.002 |
| Alternate Webpage(s) | https://istina.msu.ru/media/publications/article/eec/f8f/25832630/On-line_issue-2016.pdf |
| Alternate Webpage(s) | https://doi.org/10.1016/j.phpro.2016.05.002 |
| Volume Number | 82 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
