NDLI: A chemical free, nanotechnology-based method for airborne bacterial inactivation using engineered water nanostructures.

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A chemical free, nanotechnology-based method for airborne bacterial inactivation using engineered water nanostructures.

Content Provider	Semantic Scholar
Author	Pyrgiotakis, Georgios Mcdevitt, James J. Bordini, André Diaz, Edgar A. Molina, Ramon M. Watson, Christa Y. DeLoid, Glen M. Lenard, Steve Fix, Natalie R. Mizuyama, Yosuke Yamauchi, Toshiyuki Brain, Joseph D. Demokritou, Philip
Copyright Year	2014
Abstract	Airborne pathogens are associated with the spread of infectious diseases and increased morbidity and mortality. Herein we present an emerging chemical free, nanotechnology-based method for airborne pathogen inactivation. This technique is based on transforming atmospheric water vapor into Engineered Water Nano-Structures (EWNS) via electrospray. The generated EWNS possess a unique set of physical, chemical, morphological and biological properties. Their average size is 25 nm and they contain reactive oxygen species (ROS) such as hydroxyl and superoxide radicals. In addition, EWNS are highly electrically charged (10 electrons per particle on average). A link between their electric charge and the reduction of their evaporation rate was illustrated resulting in an extended lifetime (over an hour) at room conditions. Furthermore, it was clearly demonstrated that the EWNS have the ability to interact with and inactivate airborne bacteria. Finally, inhaled EWNS were found to have minimal toxicological effects, as illustrated in an acute in-vivo inhalation study using a mouse model. In conclusion, this novel, chemical free, nanotechnology-based method has the potential to be used in the battle against airborne infectious diseases.
Starting Page	15
Ending Page	26
Page Count	12
File Format	PDF HTM / HTML
DOI	10.1039/C3EN00007A
PubMed reference number	26180637
Journal	Medline
Volume Number	2014
Issue Number	1
Alternate Webpage(s)	http://www.rsc.org/suppdata/en/c3/c3en00007a/c3en00007a.pdf
Alternate Webpage(s)	https://stacks.cdc.gov/view/cdc/32216/cdc_32216_DS1.pdf
Alternate Webpage(s)	https://doi.org/10.1039/C3EN00007A
Journal	Environmental science. Nano
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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