NDLI: CCR 20th Anniversary Commentary: Circulating Tumor Cells in Prostate Cancer.

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CCR 20th Anniversary Commentary: Circulating Tumor Cells in Prostate Cancer.

Content Provider	Semantic Scholar
Author	Mehra, Niven Zafeiriou, Zafeiris Lorente, David Sánchez Terstappen, Leon W. M. M. Bono, Johann S. De
Copyright Year	2015
Abstract	Circulating tumor cells (CTC) have substantial promise for multipurpose biomarker studies in prostate cancer. The IMMC-38 trial conducted by de Bono and colleagues, which was published in the October 1, 2008, issue of Clinical Cancer Research, demonstrated for the first time that CTCs are the most accurate and independent predictor of overall survival in metastatic prostate cancer. Since the publication of prospective trials demonstrating prognostic utility, CTCs have been utilized for nucleic acid analyses, for protein analyses, and in intermediate endpoint studies. CTC studies are also now facilitating the analysis of intrapatient heterogeneity. See related article by de Bono et al., Clin Cancer Res 2008;14(19) October 1, 2008;6302-9.
Starting Page	1265
Ending Page	1273
Page Count	9
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://clincancerres.aacrjournals.org/content/clincanres/21/22/4992.full.pdf
PubMed reference number	26567358v1
Alternate Webpage(s)	https://doi.org/10.1158/1078-0432.CCR-14-3129
DOI	10.1158/1078-0432.ccr-14-3129
Journal	Clinical cancer research : an official journal of the American Association for Cancer Research
Volume Number	21
Issue Number	22
Language	English
Access Restriction	Open
Subject Keyword	Biological Markers CCR Receptors Cell Nucleus Genetic Heterogeneity Malignant neoplasm of prostate Nucleic Acids Prostate carcinoma Prostatic Neoplasms Published Comment Scientific Publication
Content Type	Text
Resource Type	Article

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