Comparison of Matrix Assisted Laser Desorption / Ionization Mass Spectrometry with Electrospray Ionisation Mass Spectrometry for the characterisation of semi-telechelic polyethylene oxide

Content Provider	Semantic Scholar
Author	Winter, Julien De Vachaudez, Magali Coulembier, Olivier Dubois, Philippe Francois Flammang, Robert Gerbaux, Pascal
Copyright Year	2010
Abstract	MALDI-MS methodology is nowadays considered as a very reliable technique to determine the chemical structures and the molecular weight distribution of a synthetic polymer. At variance, ESI-MS occupies only a small segment in the analysis of polymers mainly because of the formation of multiple charged ion distributions, which interfere with the molecular distribution in the mass spectra of synthetic polymers. In the present communication, we want to demonstrate that, when applied to fragile polymer samples, both techniques can lead to misinterpretation since in source decomposition of the ionized oligomers can sometimes not be avoided. An accurate knowledge of the source parameters and their influences is therefore a prerequisite prior to start the analysis of the MS data. Moreover, we would like to propose that the best MS methodology to analyze fragile synthetic polymers is to associate the data obtained by both the MALDI-MS and ESI-MS techniques.
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Alternate Webpage(s)	https://docnum.umons.ac.be/Access/WebOpenAccess/GetDocument.aspx?Filename=396+Dubois+et+al+e-Polymers+2010+103+1_10.pdf&GuidTicket=8c8389aa-7c86-414b-a5b8-c299db87875b
Language	English
Access Restriction	Open
Subject Keyword	Charge (electrical) Ions Molecular Weight Polyethylene Glycols Polymers Sample Variance Semiconductor industry Spectrometry Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Synthetic Polymer Synthetic data Synthetic intelligence
Content Type	Text
Resource Type	Article