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Radical alkylation of isocyanides with amino acid-/peptide-derived Katritzky salts via photoredox catalysis.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Zhang, Miao-Miao Liu, Feng |
| Copyright Year | 2019 |
| Abstract | An efficient and mild method was developed for the synthesis of 6-alkylated phenanthridines upon visible light irradiation. Bench-stable and easily handled redox-active Katritzky pyridinium salts derived from abundant amino acids/peptides were used as radical precursors for the alkylation of isocyanobiphenyl species. The reaction displays an excellent functional group tolerance and a potential utility for peptide functionalization, allowing access to desired products in good to excellent yields. |
| Starting Page | 1531 |
| Ending Page | 1534 |
| Page Count | 4 |
| File Format | PDF HTM / HTML |
| DOI | 10.1039/c8ob02786b |
| PubMed reference number | 30681112 |
| Journal | Medline |
| Volume Number | 17 |
| Issue Number | 6 |
| Alternate Webpage(s) | http://www.rsc.org/suppdata/c8/ob/c8ob02786b/c8ob02786b1.pdf |
| Alternate Webpage(s) | https://doi.org/10.1039/c8ob02786b |
| Journal | Organic & biomolecular chemistry |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |