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Taking enzyme kinetics out of control; putting control into regulation.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Hofmeyr, Jan-Hendrik S. Cornish-Bowden, Athel Rohwer, Johann M. |
| Copyright Year | 1993 |
| Abstract | The matrix formulation of metabolic control analysis, which states that multiplying the elasticity matrix for any system by the corresponding control matrix yields an identity matrix, can be transformed into a statement that multiplying a matrix expressing internal regulatory properties by a matrix expressing external regulatory properties also yields an identity matrix. This transformation supplies the formal basis for metabolic regulation analysis, and provides the key to determining the control structure of a system without the need to know the exact changes in enzyme activities that are made to measure control coefficients. |
| File Format | PDF HTM / HTML |
| DOI | 10.1111/j.1432-1033.1993.tb17725.x |
| PubMed reference number | 8462553 |
| Journal | Medline |
| Volume Number | 212 |
| Issue Number | 3 |
| Alternate Webpage(s) | http://bip.cnrs-mrs.fr/bip10/OutControl93.pdf |
| Alternate Webpage(s) | https://doi.org/10.1111/j.1432-1033.1993.tb17725.x |
| Journal | European journal of biochemistry |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
