NDLI: Fe 3 O 4 and Fe 3 O 4 @ Au Nanoparticles : Synthesis and Functionalisation for Biomolecular Attachment

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Fe 3 O 4 and Fe 3 O 4 @ Au Nanoparticles : Synthesis and Functionalisation for Biomolecular Attachment

Content Provider	Semantic Scholar
Author	Walt, Hendriëtte Van Der Chown, Lesley Hearth Harris, Richard Sosibo, Ndabenhle Tshikhudo, Robert
Copyright Year	2012
Abstract	The use of magnetic and magnetic/gold core/shell nanoparticles in biotechnology or medicine has shown good promise due to their hybrid nature which possesses superior magnetic and optical properties. Some of these potential applications include hyperthermia treatment, bio-separations, diagnostics, drug delivery and toxin removal. Synthesis refinement to control geometric and magnetic/optical properties, and finding functional surfactants for biomolecular attachment, are requirements to meet application specifics. Various high-temperature preparative methods were used for the synthesis of iron oxide and gold-coated iron oxide nanoparticles. Different surface functionalities, such as 11-aminoundecanoic and 11-mercaptoundecanoic acid, were introduced on the surface of the particles to facilitate further attachment of biomolecular functionality and drug-like molecules. Nanoparticle thermal stability, composition, state of aggregation, size and morphology were investigated and the results from techniques such as Fourier Transform-Infra Red spectroscopy (FT-IR), Ultraviolet visible spectroscopy (UV-vis), Transmission Electron Microscopy (TEM) and thermal analysis are discussed. Keywords—Core/shell, Iron oxide, Gold coating, Nanoparticles.
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.waset.org/journals/waset/v44/v44-174.pdf
Alternate Webpage(s)	http://waset.org/publications/7836/fe3o4-and-fe3o4-au-nanoparticles-synthesis-and-functionalisation-for-biomolecular-attachment
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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