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Reduction in false-positive Aspergillus serum galactomannan enzyme immunoassay results associated with use of piperacillin-tazobactam in the United States.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Vergidis, Paschalis I. Razonable, Raymund R. Wheat, Lawrence Joseph Estes, Lynn L. Caliendo, Angela M. Baden, Lindsey Robert Wingard, John R. Baddley, John W. Assi, M. H. Ake Norris, Steven Mark Chandrasekar, Pranatharthi Shields, Ryan K. Nguyen, Thi Khanh Freifeld, Alison G. Kohler, Richard C. Kleiman, Martin B. Walsh, Thomas J. Hage, Chadi A. |
| Copyright Year | 2014 |
| Abstract | Piperacillin-tazobactam (PTZ) is known to cause false-positive results in the Platelia Aspergillus enzyme-linked immunoassay (EIA), due to contamination with galactomannan (GM). We tested 32 lots of PTZ and 27 serum specimens from patients receiving PTZ. GM was not detected in the lots of PTZ; one serum specimen (3.7%) was positive. PTZ formulations commonly used in the United States today appear to be a rare cause for false-positive GM results. |
| Starting Page | 3802 |
| Ending Page | 3802 |
| Page Count | 1 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://jcm.asm.org/content/52/6/2199.full.pdf?legid=jcm%3B52/6/2199&related-urls=yes |
| PubMed reference number | 24719434v1 |
| Alternate Webpage(s) | https://doi.org/10.1128/JCM.00285-14 |
| DOI | 10.1128/jcm.00285-14 |
| Journal | Journal of clinical microbiology |
| Volume Number | 52 |
| Issue Number | 6 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Aspergillus CDISC SEND Biospecimens Terminology Enzyme Immunoassay Immunoenzyme Procedure Patients Piperacillin Specimen galactomannan piperacillin-tazobactam combination tazobactam |
| Content Type | Text |
| Resource Type | Article |