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Feasibility of Arthroscopic Indentation Measurements for in Vivo Evaluation of Human Knee Joint Articular Cartilage
| Content Provider | Semantic Scholar |
|---|---|
| Copyright Year | 2005 |
| Abstract | INTRODUCTION: Several laboratory studies [1,2] have suggested that mechanical indentation measurements can offer diagnostic information on cartilage integrity not reachable during qualitative arthroscopy. However, arthroscopic in vivo measurement of cartilage stiffness presents several challenges not present in laboratory testing. In this study, we tested in vivo feasibility of two models of commercial indentation instrument [3]. MATERIALS AND METHODS: First, elastomer samples with varying stiffness and thickness were tested in a laboratory to compare indentation characteristics of two models of a commercial, clinically used indentation instrument (Artscan (AS) 1000 and 200, Artscan Ltd, Helsinki, Finland). As both models are still in use there is a need to characterize possible differences. AS 1000, but not AS 200, has been extensively tested in laboratory. Therefore, prior to in vivo testing, AS 200 was tested in situ with bovine cartilage. Subsequently, the arthroscopic indentation measurements were conducted independently by two surgeons in Finland (AS 1000, n = 20) and USA (AS 200, n = 18). Measurement sites were located at the center of lateral and medial femoral condyles (LFC, FMC) and tibial plateaus (LTP, MTP). Mean age of the patients was 30.7±10.1 years, BMI ranged 18.8-38.8 (mean 26.4). Cartilage surfaces of the knee were evaluated visually by using the guidelines of ICRS [4]. While the difference between the cartilage visual grades 0 (normal) and 1 (superficial lesions, minor superficial fissures and cracks, softening) depends subjectively on the surgeon’s decision, all patients with ICRS grade 0 and 1 were accepted for the study. For the in vivo indentation measurements, a portal was made on a side of the patellar ligament and the measurement rod of the indentation instrument was inserted into the knee joint (Fig. 1). The arthroscopic measurements were systematically conducted twice at both sites of the knee to enable analysis of measurement reproducibility (root mean squared coefficient of variation (CV)). Kruskall-Wallis post hoc test was used to compare the differences in indentation stiffness between the measurement sites. The study was approved by the local authorities and patients underwent informed consent at both sites. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.ors.org/Transactions/52/0750.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
