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Regulation of phospholipid biosynthesis in Saccharomyces cerevisiae by cyclic AMP-dependent protein kinase.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Kinney, Anthony J. Bae-Lee, M. S. Panghaal, S. S. Kelley, Michael J. Gaynor, P. M. Carman, George M. |
| Copyright Year | 1990 |
| Abstract | The addition of cyclic AMP (cAMP) to Saccharomyces cerevisiae cyr1 mutant cells resulted in an increase in the rate of phosphatidylinositol synthesis at the expense of phosphatidylserine synthesis. The decrease in phosphatidylserine synthesis correlated with the down regulation of phosphatidylserine synthase activity by cAMP-dependent protein kinase phosphorylation. The increase in phosphatidylinositol synthesis was not due to the regulation of phosphatidylinositol synthase by cAMP-dependent protein kinase. |
| Starting Page | 174 |
| Ending Page | 181 |
| Page Count | 8 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://jb.asm.org/content/172/2/1133.full.pdf |
| PubMed reference number | 2153654v1 |
| Volume Number | 172 |
| Issue Number | 2 |
| Journal | Journal of bacteriology |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Anabolism CDP-Diacylglycerol-Inositol 3-Phosphatidyltransferase CDP-diacylglycerol-serine O-phosphatidyltransferase activity Cyclic AMP Down-Regulation Phosphatidylserine Synthase Phosphatidylserines Phospholipids Protein Kinases eIF-2 Kinase phosphatidylinositol biosynthetic process phosphatidylserine biosynthetic process phospholipid biosynthetic process |
| Content Type | Text |
| Resource Type | Article |