NDLI: Vascular filters of functional MRI: spatial localization using BOLD and CBV contrast.

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Vascular filters of functional MRI: spatial localization using BOLD and CBV contrast.

Content Provider	Semantic Scholar
Author	Mandeville, Joseph B. Marota, John J. A.
Copyright Year	1999
Abstract	The spatial distributions of functional activation of rat somatosensory cortex by forepaw stimulation were quantitatively compared using blood oxygen level dependent (BOLD) signal and signal weighted by cerebral blood volume (CBV). The BOLD contrast to noise (CNR) distribution showed a significant dorsal shift with respect to the CBV method at fields strengths of 2 T (0.69 +/- 0.09 mm) and 4.7 T (0.44 +/- 0.15 mm). These shifts were attributed to the gradient of resting state blood volume across somatosensory cortex and the different CNR characteristics of the two image methods. The underlying principles suggest that the CBV method has a more uniform sensitivity to percent changes in functional indicators (blood volume or deoxygenated hemoglobin) across regions of variable resting state CBV. Magn Reson Med 42:591-598, 1999.
Starting Page	673
Ending Page	676
Page Count	4
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.martinos.org/~jbm/vascular_filters.pdf
Alternate Webpage(s)	http://spin.ecn.purdue.edu/fmri/PDFLibrary/MandevilleJ_MRM_1999_42_591_598.pdf
PubMed reference number	10467305v1
Volume Number	42
Issue Number	3
Journal	Magnetic resonance in medicine
Language	English
Access Restriction	Open
Subject Keyword	Cerebral Blood Volume Cerebral cortex Deoxyhemoglobin Percent (qualifier value) Rest Somatosensory Cortex blood oxygen level dependent
Content Type	Text
Resource Type	Article

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