NDLI: Amyotrophic Lateral Sclerosis with Dementia Case Report

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Amyotrophic Lateral Sclerosis with Dementia Case Report

Content Provider	Semantic Scholar
Author	Brito-Marques, Paulo Roberto De Mello, Roberto José Vieira De
Abstract	A patient is described in whom a profound and rapidly progressive dementia occurred in association with clinical features of amyotrophic lateral sclerosis. A magnetic resonance imaging showed signs of frontal and especially left temporal atrophy. The pattern of dementia indicated impaired frontotemporal lobe functions, evidenced by reduced tracer uptake in the frontotemporal lobes on brain single photon emission computed tomography. Neuropathological examination in this patient revealed mild frontotemporal atrophy with spongiform changes and neuronal loss affecting mainly layers II and III of the frontotemporal cortices. There was atrophy of the hypoglossal nuclei. The spinal cord changes were consistent with motor neuron disease. The patient showed an irreversible and progressive course. A review of the relevant literature was made.
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.scielo.br/pdf/anp/v57n2A/1481.pdf
Alternate Webpage(s)	http://neurologiapaulobrito.com/artigos/Brito-Marques1.pdf
Language	English
Access Restriction	Open
Subject Keyword	Acoustic lobing Amyotrophic Lateral Sclerosis Atrophic CT scan Epilepsy, Temporal Lobe Frontotemporal dementia Lateral thinking Motor Neuron Disease Motor Neurons Multiple Sclerosis Patients Photons Resonance Spinal Cord Tomography, Emission-Computed Tomography, Emission-Computed, Single-Photon Tracer X-Ray Computed Tomography anatomical layer
Content Type	Text
Resource Type	Article

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