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Neural correlates of reexperiencing, avoidance, and dissociation in PTSD: symptom dimensions and emotion dysregulation in responses to script-driven trauma imagery.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Hopper, James W. Frewen, Paul A. Kolk, Bessel A. Van Der Lanius, Ruth A. |
| Copyright Year | 2007 |
| Abstract | Research suggests that responses to script-driven trauma imagery in posttraumatic stress disorder (PTSD) include reexperiencing and dissociative symptom subtypes. This functional magnetic resonance imaging (fMRI) study employed a dimensional approach to characterizing script-driven imagery responses, using the Responses to Script-Driven Imagery Scale and correlational analyses of relationships between severity of state posttraumatic symptoms and neural activation. As predicted, state reexperiencing severity was associated positively with right anterior insula activity and negatively with right rostral anterior cingulate cortex (rACC). Avoidance correlated negatively with rACC and subcallosal anterior cingulate activity. In addition, as predicted, dissociation correlated positively with activity in the left medial prefrontal and right superior temporal cortices, and negatively with the left superior temporal cortex. Theoretical and clinical implications are discussed, particularly with respect to an emotion-dysregulation account of PTSD. |
| File Format | PDF HTM / HTML |
| DOI | 10.1002/jts.20284 |
| PubMed reference number | 17955540 |
| Journal | Medline |
| Volume Number | 20 |
| Issue Number | 5 |
| Alternate Webpage(s) | http://www.traumacenter.org/products/pdf_files/Neural_correlates.pdf |
| Alternate Webpage(s) | https://www.jimhopper.com/pdf/hopper_et_al_(2007)_neural_correlates_of_reexp_avoid_dissoc_in_ptsd.pdf |
| Alternate Webpage(s) | https://doi.org/10.1002/jts.20284 |
| Journal | Journal of traumatic stress |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |