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Miocene DNA sequences — a dream come true?
| Content Provider | Semantic Scholar |
|---|---|
| Author | Pääbo, S. Wilson, Allan Charles |
| Copyright Year | 1991 |
| Abstract | The advent of the polyrnerase chain reaction (PCR) is transforming many aspects of molecular biology. An example of this is the field of ‘molecular archaeology’ the retrieval of DNA sequences from ancient tissues which owes its very existence to this technique [ 11. The ability of the PCR to amplify a few intact DNA molecules that are extracted from old tissues has for the first time ‘made it possible to go back in time and study old DNA sequences. Indeed, the PCR can even recreate longer sequences from short fragments in the test tube [2]. Thus, we can now dream :about catching molecular evolution red-handed. So far, dlreams about this sort of time travel have come true only for short trips into the past. Until recently, the oldest DNA sequences determined were 40000-year-old mammoth sequences (RG. Higuchi, unpublished results). |
| Starting Page | 45 |
| Ending Page | 46 |
| Page Count | 2 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/0960-9822(91)90125-G |
| PubMed reference number | 15336206 |
| Journal | Medline |
| Volume Number | 1 |
| Alternate Webpage(s) | https://www.eva.mpg.de/fileadmin/content_files/staff/paabo/pdf/Paabo_Miocene_CurrBiol_1991.pdf |
| Alternate Webpage(s) | https://www.eva.mpg.de/documents/Elsevier/P%C3%A4%C3%A4bo_Miocene_CurrBiol_1991_2110550.pdf |
| Alternate Webpage(s) | https://api.elsevier.com/content/article/pii/096098229190125G |
| Alternate Webpage(s) | https://www.sciencedirect.com/science/article/pii/096098229190125G?dgcid=api_sd_search-api-endpoint |
| Alternate Webpage(s) | https://doi.org/10.1016/0960-9822%2891%2990125-G |
| Journal | Current Biology |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
