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Relationship between Blood Mercury Concentration and Bone Mineral Density in Korean Men in the 2008–2010 Korean National Health and Nutrition Examination Survey
| Content Provider | Semantic Scholar |
|---|---|
| Author | Kim, Yang Hee Shim, Jae Yong Seo, Min Seok Yim, Hyung Ji |
| Copyright Year | 2016 |
| Abstract | BACKGROUND The results of previous studies on the association between blood mercury (Hg) and bone mineral density (BMD) are inconsistent. We therefore used a large-scale nationwide representative sample of Korean men to investigate the relationship between these two parameters. METHODS A nationwide cross-sectional study was conducted using data from the 2008 to 2010 Korean National Health and Nutrition Examination Survey to evaluate the relationship between blood Hg and BMD and the prevalence of osteopenia or osteoporosis in 1,190 men over 50 years of age. BMD was measured by dual-energy X-ray absorptiometry. Osteopenia and osteoporosis were diagnosed for each body site according to World Health Organization T-score criteria. RESULTS After adjusting for age, body mass index, caloric energy and calcium intake, vitamin D levels, fish consumption, alcohol consumption, smoking, and exercise, quartiles of blood Hg were positively associated with femur neck T-scores in multiple linear regression analysis (β=0.06, P-value=0.03). Compared with the lowest blood Hg quartile, the odds ratios and 95% confidence intervals for diagnosis of osteopenia or osteoporosis in the second and fourth quartiles were 0.63 (0.41-0.99) and 0.57 (0.36-0.91), respectively, in the femur neck after adjusting for the same co-variables. CONCLUSION High blood Hg levels were associated with reduced odds of decreased femur neck BMD in Korean men. However, subgroup analysis did not show a significant protective effect of blood Hg on osteoporotic fractures. Further research is necessary to clarify the association between blood Hg and BMD. |
| Starting Page | 273 |
| Ending Page | 278 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| DOI | 10.4082/kjfm.2016.37.5.273 |
| PubMed reference number | 27688860 |
| Journal | Medline |
| Volume Number | 37 |
| Journal | Korean journal of family medicine |
| Alternate Webpage(s) | https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ae/5d/kjfm-37-273.PMC5039118.pdf |
| Alternate Webpage(s) | https://doi.org/10.4082/kjfm.2016.37.5.273 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
