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Neural input and neural control of the subcommissural organ.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Jiménez, Antonio Jesús Fernández-Llébrez, Pedro Pérez-Fígares, José Manuel |
| Copyright Year | 2001 |
| Abstract | The neural control of the subcommissural organ (SCO) has been partially characterized. The best known input is an important serotonergic innervation in the SCO of several mammals. In the rat, this innervation comes from raphe nuclei and appears to exert an inhibitory effect on the SCO activity. A GABAergic innervation has also been shown in the SCO of the rat and frog Rana perezi. In the rat, GABA and the enzyme glutamate decarboxylase are involved in the SCO innervation. GABA is taken up by some secretory ependymocytes and nerve terminals, coexisting with serotonin in a population of synaptic terminals. Dopamine, noradrenaline, and different neuropeptides such as LH-RH, vasopressin, vasotocin, oxytocin, mesotocin, substance P, alpha-neoendorphin, and galanin are also involved in SCO innervation. In the bovine SCO, an important number of fibers containing tyrosine hydroxylase are present, indicating that in this species dopamine and/or noradrenaline-containing fibers are an important neural input. In Rana perezi, a GABAergic innervation of pineal origin could explain the influence of light on the SCO secretory activity in frogs. A general conclusion is that the SCO cells receive neural inputs from different neurotransmitter systems. In addition, the possibility that neurotransmitters and neuropeptides present in the cerebrospinal fluid may also affect the SCO activity, is discussed. |
| Starting Page | 91 |
| Ending Page | 96 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://atarazanas.sci.uma.es/docs/articulos/16667694.pdf |
| PubMed reference number | 11241862v1 |
| Volume Number | 52 |
| Issue Number | 5 |
| Journal | Microscopy research and technique |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Adrenergic alpha-Agonists Anura Bos taurus Carboxy-Lyases Cell secretion Cerebrospinal Fluid Decussation Dopamine Galanin Glutamate Decarboxylase Glutamic Acid Gonadorelin Mammals Mixed Function Oxygenases Nerve Endings Neurotransmitters Norepinephrine Oxytocin Pineal gland Presynaptic Terminals Serotonin Spindle Cell Oncocytoma of the Adenohypophysis Structure of subcommissural organ TH gene Tissue fiber Tyrosine Vasotocin gamma-Aminobutyric Acid mesotocin nerve supply physical hard work raphe nuclei |
| Content Type | Text |
| Resource Type | Article |
