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Application of terahertz spectroscopy to the characterization of biological samples using birefringence silicon grating.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Saha, Shimul Chandra Grant, James P. Ma, Yong Khalid, Ata Feng Cumming, David R. S. |
| Copyright Year | 2012 |
| Abstract | We present a device and method for performing vector transmission spectroscopy on biological specimens at terahertz (THz) frequencies. The device consists of artificial dielectric birefringence obtained from silicon microfluidic grating structures. The device can measure the complex dielectric function of a liquid, across a wide THz band of 2 to 5.5 THz, using a Fourier transform infrared spectrometer. Measurement data from a range of liquid specimens, including sucrose, salmon deoxyribonucleic acid (DNA), herring DNA, and bovine serum albumin protein solution in water are presented. The specimen handling is simple, using a microfluidic channel. The transmission through the device is improved significantly and thus the measurement accuracy and bandwidth are increased. |
| Starting Page | 067006 |
| Ending Page | 067006 |
| Page Count | 1 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://eprints.gla.ac.uk/65873/1/65873.pdf |
| PubMed reference number | 22734784v1 |
| Alternate Webpage(s) | https://doi.org/10.1117/1.JBO.17.6.067006 |
| DOI | 10.1117/1.JBO.17.6.067006 |
| Journal | Journal of biomedical optics |
| Volume Number | 17 |
| Issue Number | 6 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Bands Birefringence Bos taurus CDISC SEND Biospecimens Terminology DNA Fill Handling (Psychology) Liquid substance Microfluidics Serum Albumin, Bovine Silicon Silicon:SCnt:Pt:Tiss:Qn Solutions Specimen processing (procedure) Spectrometers Spectroscopy, Fourier Transform Infrared Spectroscopy, Near-Infrared Sucrose Terahertz Thioctic Acid Vector Transmission disease transmission |
| Content Type | Text |
| Resource Type | Article |