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Cetuximab in the treatment of advanced non-small cell lung cancer: FISHing for a miraculous catch.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Landi, Lorenza Rossi, Antonio |
| Copyright Year | 2018 |
| Abstract | Non-small cell lung cancer (NSCLC) is divided in two main histologies: non-squamous and squamous histotypes. In metastatic non-squamous NSCLC patients, the oncogene-addicted subgroups are characterized by the presence of epidermal growth factor receptor (EGFR), anaplastic lymphoma kinase (ALK) and proto-oncogene tyrosine-protein kinase 1 (ROS1) deregulations which can benefit, in the current practice, by specific tyrosine kinase inhibitors (TKIs). |
| Starting Page | S1940 |
| Ending Page | S1944 |
| Page Count | 1 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://jtd.amegroups.com/article/download/20790/pdf |
| PubMed reference number | 30023086v1 |
| Alternate Webpage(s) | https://doi.org/10.21037/jtd.2018.04.126 |
| DOI | 10.21037/jtd.2018.04.126 |
| Journal | Journal of thoracic disease |
| Volume Number | 10 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | ALK protein, human Biological Markers CD274 wt Allele Cell Proliferation Growth Factor Receptors Histology Immunohistochemistry Ligands Lymphoma Lymphoma, Non-Hodgkin Monoclonal Antibodies Mutation Neoplasms Non-Small Cell Lung Carcinoma Oncogenes Orally Disintegrating Tablet Dosage Form Overall Survival Parkinson Disease Patients Platinum Progression-Free Survival Protein Kinases Protein Tyrosine Kinase Proto-Oncogenes ROS1 protein, human Small cell carcinoma of lung Squamous cell carcinoma Squamous cell lung carcinoma Subgroup A Nepoviruses Tyrosine Kinase Inhibitors [MoA] cetuximab necitumumab pembrolizumab |
| Content Type | Text |
| Resource Type | Article |
