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Autotaxn Inhibitors Cross-reference to Related Applications
| Content Provider | Semantic Scholar |
|---|---|
| Author | Javanmard, Sahar |
| Copyright Year | 2017 |
| Abstract | Classes of compounds that exhibit effective inhibition of autotaxin enzymes are provided. Such classes include thio ureas, diphenyldiazerenes, Xanthenes, and isoindoles and exhibit reactivity with autotaxin to ultimately reduce the size of the reactive sites thereon to prevent conversion of lyso phosphatidylcholine to lysophophatidic acid. Furthermore, such compounds can be incorporated within delivery forms for human ingestion. As such, these compounds accord an excellent manner of potentially reducing generation of cer tain cancers attributable to the presence of naturally occurring autotaxin within the human body. Methods of inactivating autotaxin to certain degrees therewith Such compounds are encompassed within invention as well. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://www.memphis.edu/fedex/ott/patentspdfs/us8969590.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
