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The synthesis of new amphiphilic p-tert-butylthiacalix[4]arenes containing peptide fragments and their interaction with DNA.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Padnya, Pavel Andreyko, Elena A. Mostovaya, Olga A. Rizvanov, Ildar Kh Stoikov, Ivan I. |
| Copyright Year | 2015 |
| Abstract | New water-soluble p-tert-butylthiacalix[4]arenes containing peptide and quaternary ammonium fragments in cone and 1,3-alternate conformations were synthesized and characterized. The interaction of the macrocycles with DNA was studied by UV-spectroscopy, DLS and TEM. It was shown that the interaction of the self-associates based on p-tert-butylthiacalix[4]arenes tetrasubstituted at the lower rim with glycine and quaternary ammonium fragments in cone and 1,3-alternate conformations with DNA led to the formation of particles of about 99-192 nm in size. |
| File Format | PDF HTM / HTML |
| DOI | 10.1039/c5ob00548e |
| PubMed reference number | 25921225 |
| Journal | Medline |
| Volume Number | 13 |
| Issue Number | 21 |
| Alternate Webpage(s) | http://www.rsc.org/suppdata/c5/ob/c5ob00548e/c5ob00548e1.pdf |
| Alternate Webpage(s) | https://doi.org/10.1039/c5ob00548e |
| Journal | Organic & biomolecular chemistry |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |