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Predictors of outcome and severity in adult filipino patients with febrile neutropenia
| Content Provider | Semantic Scholar |
|---|---|
| Author | Villalobos, Rem Berba, Rp Juan-Bartolome, Mmj |
| Copyright Year | 2015 |
| Abstract | Aim. The study aimed to describe the profile of Filipino febrile neutropenia patients and to determine parameters associated with severe outcomes. Methods. This is a retrospective study of Filipino febrile neutropenia patients admitted to the Philippine General Hospital. Patients were described in terms of clinical presentation and stratified according to the presence or absence of severe outcomes. Prognostic factors were then identified using regression analysis. Results. 115 febrile episodes in 102 patients were identified. Regression analysis yielded prolonged fever >7 days prior to admission (OR 2.43; 95% CI, 0.77–7.74), isolation of a pathogen on cultures (OR 2.69; 95% CI, 1.04–6.98), and nadir absolute neutrophil count (ANC) 7 days prior to admission, positive pathogen on cultures, and nadir ANC < 100 during admission predicted severe outcomes, whereas G-CSF use and complete antibiotic therapy were associated with better outcomes. These prognostic variables might be useful in identifying patients that need more intensive treatment and monitoring. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://downloads.hindawi.com/journals/ah/2015/920838.pdf |
| Alternate Webpage(s) | https://icm-experimental.springeropen.com/track/pdf/10.1186/2197-425X-3-S1-A253 |
| Alternate Webpage(s) | http://ftp.ncbi.nlm.nih.gov/pub/pmc/0a/e5/AH2015-920838.PMC4573217.pdf |
| PubMed reference number | 27289785v1 |
| Alternate Webpage(s) | https://doi.org/10.1186/2197-425X-3-S1-A253 |
| DOI | 10.1186/2197-425X-3-S1-A253 |
| Journal | Intensive Care Medicine Experimental |
| Volume Number | 3 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Absolute neutrophil count Antibiotic therapy Antibiotics Colony-Stimulating Factors Febrile Neutropenia Fever Filgrastim Granulocyte Colony-Stimulating Factor Neutrophil count (procedure) Pathogenic organism Patients Stimulation (motivation) |
| Content Type | Text |
| Resource Type | Article |