Surgical management of the recurrence and regrowth of craniopharyngiomas.

Content Provider	Semantic Scholar
Author	Minamida, Yoshihiro Mikami, Takeshi Hashi, Kazuo Houkin, Kiyohiro
Copyright Year	2005
Abstract	OBJECT The authors performed a retrospective analysis of a consecutive series of craniopharyngiomas and their recurrences, which were managed with surgery alone. METHODS In the past 20 years, 37 consecutive patients with craniopharyngiomas underwent surgery without adjuvant radiotherapy. During that period there was a consistent strategy that surgical management was the first choice of treatment whenever possible. Of these 37 patients, 11 experienced tumor recurrence (29.7%) during the mean follow-up period of 11.1 years. Of these 11 patients, seven experienced recurrence after neuroimaging-confirmed total removal, and four patients experienced recurrence after partial or incomplete removal. In these 11 patients, surgical removal was performed 17 times. Using a proper surgical approach (mainly a basal interhemispheric approach) and meticulous microsurgical techniques, total removal of the recurrent tumor was achieved in nine surgeries (52.9). The mortality and morbidity rates associated with these 17 surgeries were 0% and 9.1%, respectively. In most cases, visual function was preserved or improved and intellectual performance was also preserved. CONCLUSIONS Recurrence of craniopharyngioma can be safely managed by using meticulous contemporary microsurgical techniques without additional radiotherapy. The role of surgery and adjuvant radiotherapy for craniopharyngiomas may vary in the future, depending on innovations in treatment and technology. Nevertheless, surgery can be still a major therapeutic option in the management of recurrent craniopharyngiomas.
Starting Page	1232
Ending Page	1233
Page Count	2
File Format	PDF HTM / HTML
Alternate Webpage(s)	https://thejns.org/downloadpdf/journals/j-neurosurg/103/2/article-p224.pdf
Alternate Webpage(s)	http://campus.neurochirurgie.fr/Programme_Enseignement/_art1030/recurrence-Minamida.pdf
PubMed reference number	16175850v1
Volume Number	103
Issue Number	2
Journal	Journal of neurosurgery
Language	English
Access Restriction	Open
Subject Keyword	Biologic Preservation Craniopharyngioma Microsurgery Morbidity - disease rate Neoplasms Neuroimaging Operative Surgical Procedures Partial Patients Pharmaceutical Adjuvants Radiosurgery Radiotherapy, Adjuvant Recurrent Malignant Neoplasm Recurrent tumor Surgical Management Therapeutic radiology procedure Vision pediatric intracranial germ cell brain tumor
Content Type	Text
Resource Type	Article