La Kisspeptine, Un Nouvel Acteur Clé Dans Le Contrôle De La Reproduction

Content Provider	Semantic Scholar
Author	Beltramo, Massimiliano Caraty, Alain
Copyright Year	2014
Abstract	The discovery of the role of kisspeptin and of its cognate receptor, KISS1R, has been a breakthrough in the understanding of the mechanisms underpinning reproduction and in particular GnRH secretion. The injection of kisspeptin in various mammalian species showed its capacity to stimulate GnRH secretion and to trigger ovulation in anoestrus ewe. This capacity is under the control of sexual hormones that act directly and with opposite effects on the two kisspeptin neuronal populations present in the hypothalamus. There is a clear interest for the use of this molecule in farming and in human medicine although its short half-life has until now hampered its exploitation. The design of analogs with longer half-life represents a possible solution and preliminary results look promising
Starting Page	65
Ending Page	65
Page Count	1
File Format	PDF HTM / HTML
DOI	10.4267/2042/53725
Alternate Webpage(s)	http://documents.irevues.inist.fr/bitstream/handle/2042/53725/AVF_167_1_65.pdf?sequence=1
Alternate Webpage(s)	https://doi.org/10.4267/2042%2F53725
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article