NDLI: Antipsychotic Polypharmacy: State of the Science and Guidelines for Practice. It's difficult to stop once you start.

Content Provider	Semantic Scholar
Author	Bruijnzeel, Dawn M. Tandon, Rajiv
Copyright Year	2018
Abstract	espite a scanty evidence base, the concurrent use of two or more antipsychotic medications has become increasingly prevalent. The limited data on this practice provide no support for its effectiveness, except for the potential utility of adding a second antipsychotic agent to clozapine in patients with otherwise treatment-refractory schizophrenia. A number of adverse associations of antipsychotic combinations have been reported, including higher mortality, an increased risk of a range of side-effects, adverse drug interactions, decreased treatment adherence, and greater costs. We evaluate the appropriateness of the many rationales for antipsychotic combinations and outline recommendations for its place in antipsychotic therapy.
File Format	PDF HTM / HTML
DOI	10.1016/j.ajp.2018.04.024
PubMed reference number	29706178
Journal	Medline
Volume Number	33
Alternate Webpage(s)	http://medicaidmentalhealth.org/_assets/file/Summaries/TandonAntipsychoticPolypharmacy.pdf
Journal	Asian journal of psychiatry
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in