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An ATP-fueled nucleic acid signal amplification strategy for highly sensitive microRNA detection.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Wen, Zhi-Bin Liang, Wen-Bin Zhuo, Ying Xiong, Chengyi Zheng, Ying-Ning Yuan, Ruo Chai, Yaqin |
| Copyright Year | 2018 |
| Abstract | Herein, an adenosine triphosphate (ATP)-fueled nucleic acid signal amplification strategy based on toehold-mediated strand displacement (TMSD) and fluorescence resonance energy transfer (FRET) was proposed for highly sensitive detection of microRNA-21. More importantly, the target microRNA-21 could be regenerated with ATP as the fuel rather than a nucleotide segment in conventional approaches, which made the proposed strategy simple and efficient due to the high affinity and strength of the aptamer-target interaction. |
| Starting Page | 10897 |
| Ending Page | 10900 |
| Page Count | 4 |
| File Format | PDF HTM / HTML |
| DOI | 10.1039/c8cc05525d |
| Alternate Webpage(s) | http://www.rsc.org/suppdata/c8/cc/c8cc05525d/c8cc05525d1.pdf |
| PubMed reference number | 30206633 |
| Alternate Webpage(s) | https://doi.org/10.1039/c8cc05525d |
| Journal | Medline |
| Volume Number | 54 |
| Issue Number | 77 |
| Journal | Chemical communications |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |