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Direct detection of multidrug-resistant Mycobacterium tuberculosis in clinical specimens in low- and high-incidence countries by line probe assay.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Johansen, Isik Somuncu Lundgren, Bettina Sosnovskaja, Anaida Thomsen, Vibeke Østergaard |
| Copyright Year | 2003 |
| Abstract | The INNO-LiPA Rif.TB assay is designed for the detection of rpoB gene mutations causing rifampin resistance in isolates. We applied the method directly to 60 Lithuanian and Danish clinical specimens to detect rifampin resistance rapidly. Results were obtained in 78.3% of clinical specimens, and all were concordant with those obtained by BACTEC 460. The assay could have major impact on the management of multidrug-resistant tuberculosis. |
| File Format | PDF HTM / HTML |
| DOI | 10.1128/JCM.41.9.4454-4456.2003 |
| PubMed reference number | 12958292 |
| Journal | Medline |
| Volume Number | 41 |
| Issue Number | 9 |
| Alternate Webpage(s) | http://jcm.asm.org/content/41/9/4454.full.pdf |
| Alternate Webpage(s) | https://doi.org/10.1128/JCM.41.9.4454-4456.2003 |
| Journal | Journal of clinical microbiology |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |