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Atrial septal defect: waiting for symptoms remains an unsolved medical anachronism.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Berger, F. Zoltán Ewert, Peter M. |
| Copyright Year | 2011 |
| Abstract | This editorial refers to ‘Benefit of atrial septal defect closure in adults: impact of age’[†][1], by M. Humenberger et al ., on page 553 During the past decade a ‘more modern’ natural history of atrial septal defect (ASD) in adults has been written, but still the ASD remains by far the most underdiagnosed congenital heart disease in the adult age group. The moment of diagnosis within the adult population is mostly tantamount to the initiation of treatment. Due to the superiority of closure of the defect over medical treatment alone,1 the consequence is closure either by intervention in selected patients or by surgery for all unselected or at least for the remaining patients not treatable by intervention. Meanwhile supported by direct comparison of the two methods, interventional treatment in selected patients has been accepted as the standard treatment and the treatment of choice due to its lesser invasiveness and lower complication rate.2,3 The study by Humenberger et al. 4 shows nicely in a relatively large cohort of adult patients with an age range of 20–80 years that the defects were able to be closed successfully by intervention regardless of age, with excellent results and no significant complications. New York Heart Association functional class improved in almost all patients and rapid right ventricular remodelling occurred with a statistically significant improvement in right ventricular measurements and a decrease in pulmonary artery (PA) pressure levels in those with formerly elevated pressures and resistances. The authors again affirm the findings of numerous publications during the past decade and also uniformly … [1]: #fn-2 |
| Starting Page | 65 |
| Ending Page | 76 |
| Page Count | 12 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/eurheartj/32/5/10.1093/eurheartj/ehq377/2/ehq377.pdf?Expires=1491635558&Key-Pair-Id=APKAIUCZBIA4LVPAVW3Q&Signature=WorI~BawUGOKrvidcNvP9I~VPhF-GlQsTzqtlEQkYwVHr~b8n3tHf46r6GlveBWA8nluJ-N~RL9fq7oYFDOJPh7exQA0WeEHiYw8CgJUELaqPdcEyEsBW31Omsizz6CQHjm9KTQ6APAnWKlh6MTwDDUHItUZmGwC~UHcQDrp~LfYS-LgZItLpGeMVzTcie7EBr4MpVXNqR949cSUoVN~QqSAyUkhtgOzdj8U2pxi1Vk7FQYKo0L2CHBY22N3XS4jMoa1maI1IsQDjw8OC6wrZDw2Yba~M1l-Ujk9O0ZDrzfDoTjfTgYiw0SxC4XDwwzvFzcC0u6o65pwnzWq~Wc76A__ |
| PubMed reference number | 20971748v1 |
| Alternate Webpage(s) | https://doi.org/10.1093/eurheartj/ehq377 |
| DOI | 10.1093/eurheartj/ehq377 |
| Journal | European heart journal |
| Volume Number | 32 |
| Issue Number | 5 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Atrial Fibrillation Atrial Septal Defects Atrial septal aneurysm Blinded Blood supply aspects Closure Congenital heart disease Diastole Exclusion Heart Atrium Heart Diseases Heart Failure, Diastolic Heart Septal Defects Heart Ventricle Idiopathic Pulmonary Fibrosis Left ventricular structure Menopause Myocardium Natural History Patients Pulmonary artery structure Residual volume Right side of heart Right ventricular structure Trauma Severity Indices Ventricular Remodeling |
| Content Type | Text |
| Resource Type | Article |
