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Tip-enhanced fluorescence microscopy at 10 nanometer resolution.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Gerton, Jordan Mitchell Wade, Lawrence A. Lessard, Guillaume A. Ma, Ziyang Quake, Stephen R. |
| Copyright Year | 2004 |
| Abstract | We demonstrate unambiguously that the field enhancement near the apex of a laser-illuminated silicon tip decays according to a power law that is moderated by a single parameter characterizing the tip sharpness. Oscillating the probe in intermittent contact with a semiconductor nanocrystal strongly modulates the fluorescence excitation rate, providing robust optical contrast and enabling excellent background rejection. Laterally encoded demodulation yields images with <10 nm spatial resolution, consistent with independent measurements of tip sharpness. |
| Starting Page | 180801 |
| Ending Page | 180801 |
| Page Count | 1 |
| File Format | PDF HTM / HTML |
| DOI | 10.1103/PhysRevLett.93.180801 |
| PubMed reference number | 15525147 |
| Journal | Medline |
| Volume Number | 93 |
| Issue Number | 18 |
| Alternate Webpage(s) | http://www.physics.utah.edu/people/faculty/gerton/Gerton_PRL_2004.pdf |
| Alternate Webpage(s) | http://authors.library.caltech.edu/6869/1/GERprl04.pdf |
| Alternate Webpage(s) | http://diyhpl.us/~bryan/papers2/microfluidics/quake/prl-oct04.pdf |
| Alternate Webpage(s) | http://www.physics.utah.edu/~gertonlab/pdfs/gertonPhysRev2004.pdf |
| Alternate Webpage(s) | https://doi.org/10.1103/PhysRevLett.93.180801 |
| Journal | Physical review letters |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
