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Copper mediated stereoselective synthesis of C-glycosides from unactivated alkynes.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Kusunuru, Anil Kumar Tatina, Madhubabu Yousuf, Syed Khalid Mukherjee, Debaraj |
| Copyright Year | 2013 |
| Abstract | A highly stereoselective rapid C-glycosylation reaction has been developed between glycal and unactivated alkynes in the presence of coppertriflate and ascorbic acid at low catalyst loading and at room temperature. A wide variety of glycals and aryl acetylenes participate in the reaction smoothly. TfOH generated during the reduction of Cu(OTf)2 by ascorbic acid may be the active catalyst for the glycosylation. |
| File Format | PDF HTM / HTML |
| DOI | 10.1039/c3cc44250k |
| PubMed reference number | 24049771 |
| Journal | Medline |
| Volume Number | 49 |
| Issue Number | 86 |
| Alternate Webpage(s) | http://www.rsc.org/suppdata/cc/c3/c3cc44250k/c3cc44250k.pdf |
| Journal | Chemical communications |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |