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Effect of a four-week exercise program on the secretion of IFN-γ, TNF-α, IL-2 and IL-6 cytokines in elite Taekwondo athletes.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Kaya, Oktay |
| Copyright Year | 2016 |
| Abstract | The aim of the present study was to examine how a 4-week exercise program affects the serum levels of certain cytokines in Taekwondo athletes. The study involved 10 elite male Taekwondo athletes (mean age, 20.67±0.24 years; mean weight, 65.45±1.69 kg) who were studying at the Physical Education and Sports High School of Selçuk University (Konya, Turkey) in June 2014. The subjects were involved in a Taekwondo exercise program on every weekday for 4 weeks. The subjects were also engaged in an exercise to exhaustion session twice; once before starting the 4-week exercise program and once upon completion of the program. Blood samples were collected from the subjects in four rounds: During rest, upon fatigue, and before and after the 4-week exercise program. These samples were analyzed to establish the serum levels of interferon-γ (IFN-γ), tumor necrosis factor-α (TNF-α), interleukin (IL)-2 and IL-6 using enzyme-linked immunosorbent assay test kits. Pre- and post-exercise program, the IFN-γ and TNF-α levels did not show any significant difference. When compared with the pre-exercise levels, serum IL-2 levels of the subjects were found to be elevated after the 4-week exercise program. The highest serum IL-6 values were established after the subjects were exercised to fatigue before the exercise program was initiated (P<0.05). The 4-week exercise program resulted in a decrease in IL-6 levels (P<0.05). The findings of the study indicate that a 4-week exercise program did not result in significant changes in IFN-γ and TNF-α levels, but led to an increase in IL-2 levels. The notable finding of the present study is that a 4-week exercise program reduces cellular immune functions and, thus, the levels of IL-6, which negatively influences performance. |
| Starting Page | 367 |
| Ending Page | 370 |
| Page Count | 4 |
| File Format | PDF HTM / HTML |
| DOI | 10.3892/br.2016.730 |
| PubMed reference number | 27588179 |
| Journal | Medline |
| Volume Number | 5 |
| Issue Number | 3 |
| Alternate Webpage(s) | https://www.spandidos-publications.com/br/5/3/367/download |
| Alternate Webpage(s) | https://doi.org/10.3892/br.2016.730 |
| Journal | Biomedical reports |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
