NDLI: Multiple Serotonin Receptors: Too Many, Not Enough, or Just the Right Number?

Please wait, while we are loading the content...

Multiple Serotonin Receptors: Too Many, Not Enough, or Just the Right Number?

Content Provider	Semantic Scholar
Author	Uphouse, Lynda L.
Copyright Year	1997
Abstract	In this manuscript, current knowledge about central nervous system serotonin (5-HT) receptors is discussed with an emphasis toward describing the functional significance of the multiple 5-HT receptors. Five characteristics of 5-HT receptors, which are hypothesized to contribute to this functional significance, are discussed: (a) 5-HT has varying affinity and potency for the different receptor subtypes; (b) multiple transduction pathways are used by the different receptor subtypes; (c) receptor subtypes differ in their susceptibility to agonist-mediated desensitization/downregulation; (d) receptor subtypes interact in mediating cellular responses to the neurotransmitter; and (e) receptor subtypes respond differently to changes in the physiological environment. It is hypothesized that these characteristics of the multiple neurotransmitter receptors provide the nervous system with a capacity for coding and decoding of 5-HT-mediated neuronal transmission that could not take place with a single neurotransmitter receptor. Serotonergic regulation of female reproduction and regulation of glucocorticoid release are used to illustrate the integrative potential deriving from the existence of multiple 5-HT receptors.
Starting Page	679
Ending Page	698
Page Count	20
File Format	PDF HTM / HTML
DOI	10.1016/S0149-7634(96)00022-X
Alternate Webpage(s)	https://api.elsevier.com/content/article/pii/S014976349600022X
Alternate Webpage(s)	https://www.sciencedirect.com/science/article/pii/S014976349600022X?dgcid=api_sd_search-api-endpoint
PubMed reference number	9353798
Alternate Webpage(s)	https://doi.org/10.1016/S0149-7634%2896%2900022-X
Journal	Medline
Volume Number	21
Journal	Neuroscience & Biobehavioral Reviews
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Arbitrator Challenges: Too Many Or Not Enough?

A General Theory of Competition: Too Eclectic or Not Eclectic Enough? Too Incremental or Not Incremental Enough? Too Neoclassical or Not Neoclassical Enough?

Physician Workforce Projections: Too Many or Just Right?

Preprint typeset using LATEX style emulateapj v. 5/2/11 TOO MANY, TOO FEW, OR JUST RIGHT? THE PREDICTED NUMBER AND DISTRIBUTION OF MILKY WAY DWARF GALAXIES (2014)

Physician Workforce Projections: Too Many or Just Right?-Reply

Current Resident Work Hours: Too Many or Not Enough?

Not Too Hot, Not Too Cold: The Bundled-SVM is Just Right!

Not Too Hot, Not Too Cold, but “Just Right”

the source. Consumer Credit: Too Much or Too Little (or Just Right)? (2013)

Multiple Serotonin Receptors: Too Many, Not Enough, or Just the Right Number?

Similar Documents

Arbitrator Challenges: Too Many Or Not Enough?

A General Theory of Competition: Too Eclectic or Not Eclectic Enough? Too Incremental or Not Incremental Enough? Too Neoclassical or Not Neoclassical Enough?

Physician Workforce Projections: Too Many or Just Right?

Preprint typeset using LATEX style emulateapj v. 5/2/11 TOO MANY, TOO FEW, OR JUST RIGHT? THE PREDICTED NUMBER AND DISTRIBUTION OF MILKY WAY DWARF GALAXIES (2014)

Physician Workforce Projections: Too Many or Just Right?-Reply

Current Resident Work Hours: Too Many or Not Enough?

Not Too Hot, Not Too Cold: The Bundled-SVM is Just Right!

Not Too Hot, Not Too Cold, but “Just Right”

the source. Consumer Credit: Too Much or Too Little (or Just Right)? (2013)

Multiple Serotonin Receptors: Too Many, Not Enough, or Just the Right Number?