NDLI: The Pathway of Nicotinic Acid Oxidation by a Bacillus Species.

Please wait, while we are loading the content...

The Pathway of Nicotinic Acid Oxidation by a Bacillus Species.

Content Provider	Semantic Scholar
Author	Ensign, Jerald C. Rittenberg, Sydney C.
Copyright Year	1964
Abstract	Bacteria able to grow with nicotinic acid as a sole source of carbon and nitrogen have been isolated by a number of investigators (l-5). Hughes et al. (6-10) found that Pseudomonas jlzwrescens initiates degradation of nicotinic acid by a hydroxylation to form 6-hydroxynicotinic acid and established that the responsible enzyme is located in a cell wall membrane fraction. An initial hydroxylation in the 6-position was also reported by Harary (11,12) for a Clostridium species which ferments nicotinic acid, and by Behrman and Stanier (13) for a strain of P. jluorescens. The latter authors (13) showed that subsequent reactions, mediated by enzymes contained in the soluble fraction of disrupted cells, catalyze the oxidative decarboxylation of 6-hydroxynicotinic acid to 2,5-dihydroxypyridine and its cleavage to maleamic and formic acids. The former compound undergoes hydrolytic deamination to maleic acid, which is then isomerized to fumaric acid. This paper describes a different pathway of nicotinic acid oxidation utilized by a Bacillus species isolated from soil.
File Format	PDF HTM / HTML
PubMed reference number	14216418
Journal	Medline
Volume Number	239
Alternate Webpage(s)	http://www.jbc.org/content/239/7/2285.full.pdf
Alternate Webpage(s)	http://www.jbc.org/content/239/7/2285.full.pdf?origin=publication_detail
Journal	The Journal of biological chemistry
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in