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Recent advances in developing small molecules targeting RNA.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Guan, Lirui Disney, Matthew D. |
| Copyright Year | 2012 |
| Abstract | RNAs are underexploited targets for small molecule drugs or chemical probes of function. This may be due, in part, to a fundamental lack of understanding of the types of small molecules that bind RNA specifically and the types of RNA motifs that specifically bind small molecules. In this review, we describe recent advances in the development and design of small molecules that bind to RNA and modulate function that aim to fill this void. |
| Starting Page | 73 |
| Ending Page | 86 |
| Page Count | 14 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://medichem.skku.edu/erp/erpmenus/research_pds/upLoadFiles/Recent%20Advances%20in%20Developing%20Small%20Molecules%20Targeting%20RNA%20cb200447r.pdf |
| PubMed reference number | 22185671v1 |
| Alternate Webpage(s) | https://doi.org/10.1021/cb200447r |
| DOI | 10.1021/cb200447r |
| Journal | ACS chemical biology |
| Volume Number | 7 |
| Issue Number | 1 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | RNA Small Molecule Urination cellular targeting |
| Content Type | Text |
| Resource Type | Article |