NDLI: Pertussis pneumonia, hypoxemia, hyperleukocytosis, and pulmonary hypertension: improvement in oxygenation after a double volume exchange transfusion.

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Pertussis pneumonia, hypoxemia, hyperleukocytosis, and pulmonary hypertension: improvement in oxygenation after a double volume exchange transfusion.

Content Provider	Semantic Scholar
Author	Romano, Michael J. Weber, Mark D. Siu, Benjamin L.
Copyright Year	2004
Abstract	A 3-month-old infant of 33 weeks' gestation was hospitalized with pneumonia caused by Bordetella pertussis. Respiratory insufficiency worsened, and on hospital day 3, there was severe pulmonary dysfunction (arterial oxygen pressure/fraction of inspired oxygen ratio: 120), extreme leukocytosis (white blood cell count 104,000/mm3), and severe pulmonary hypertension as assessed by 2-dimensional echocardiogram. A double volume exchange transfusion was performed to reduce the leukocyte mass. Oxygenation began to improve during the exchange and continued to improve over the ensuing 31 hours (arterial oxygen pressure/fraction of inspired oxygen ratio: 280). The white blood cell count fell dramatically after the exchange, and the rate of rise was slower after exchange therapy compared with preexchange.
Starting Page	8
Ending Page	9
Page Count	2
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://pediatrics.aappublications.org/content/pediatrics/114/2/e264.full.pdf
PubMed reference number	15286267v1
Volume Number	114
Issue Number	2
Journal	Pediatrics
Language	English
Access Restriction	Open
Subject Keyword	Blood Cells Cardiovascular Diseases Cell Count Cell Respiration Cessation of life Echocardiography Exchange Transfusion, Whole Blood Fetus-to-fetus placental transfusion syndrome Hypertensive disease Hypoxia Idiopathic Pulmonary Fibrosis Idiopathic pulmonary arterial hypertension Inspiration function Leukocytes Leukocytosis Oxygen Partial Pressure Arterial Oxygen to Fraction Inspired Oxygen Ratio Measurement Patients Pertussis Vaccine Pneumocystis jiroveci pneumonia Pulmonary Hypertension Respiratory Insufficiency Shock Transfusion Reaction
Content Type	Text
Resource Type	Article

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